Anaphylaxis following vaccination in community settings: Visual aid for diagnosis and management

Organization: Public Health Agency of Canada

Date published: 2023-09-19

Related links

• EPINEPHrine dosage table
• Anaphylaxis and other acute reactions following vaccination: Canadian Immunization Guide

Know how to recognize anaphylaxis

Anaphylaxis is defined by a rapid onset of symptoms, anywhere between minutes up to 4 hours.

Distinguishing features of anaphylaxis

• Skin: urticaria, pruritus, angioedema, flushing
• Respiratory: cough, wheeze, dyspnea, bronchospasm, distress
• Gastrointestinal: nausea, vomiting, diarrhea, severe abdominal pain
• Cardiovascular: tachycardia, hypotension, syncope, dizziness, arrhythmias
• Central nervous system: irritability, sense of doom, reduced level of consciousness

If you suspect anaphylaxis

If you suspect anaphylaxis, a rapid response is critical.

Steps 1, 2, 3 and 4 should be done promptly and simultaneously.

1. Direct someone to call 9-1-1 (where available) or emergency medical services
2. Assess airway, breathing, circulation
3. Place the individual on their back and elevate lower extremities
4. Inject EPINEPHrine intramuscularly into mid-anterolateral thigh (refer to epinephrine dosage table)
5. Repeat every 5 minutes if not improving

Reference

Public Health Agency of Canada. Anaphylaxis and other acute reactions following immunization: Canadian Immunization Guide: Part 2 – Vaccine Safety Ottawa (ON): PHAC; 2020.