Follow-up assessment report on aniline: chapter 1

1. Introduction

Aniline was one of the substances included on the first Priority Substances List (PSL). Under this process, in 1994, the Government of Canada concluded that aniline was not of concern for the environment but available information was considered insufficient to conclude whether aniline was harmful to human health as defined under Paragraph 11 of Canadian Environmental Protection Act, 1988. A follow-up report was published in October 5, 2002, under CEPA 1999, for a 60-day public comment period. This report proposed that there was reason to suspect that exposure to aniline may be harmful to human health but invited stakeholders to submit relevant data to inform the conclusion as there was considerable uncertainty with respect to exposure characterization. Further information relevant to exposure characterization was subsequently identified and has been taken into consideration in current assessment. Additionally, the health effects information has been updated.

The strategy for the literature search to identify critical new data, including commercial activity in Canada, human exposure and effects is presented in Appendix A of this report. Only relevant toxicological data acquired prior to March 2009, and exposure related information developed up to June 2008, with two exceptions, SRI Consulting (2009), and ACMI (2009) were considered in this assessment.