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Why was I prescribed an antidepressant for hot flashes?

How menopause changes your brain’s thermostat

Before perimenopause (Age 20 | 30 | 40)

  • Brain thermostat = small rise in temperature
  • Normal cooling response

Perimenopause/Menopause (Age 40 | 50 | 60)

  • Brain thermostat = overheating!
  • Hot Flash – Sweating – Faster Heartbeat 

Common hot flash triggers:

  • Warm room
  • Hot drinks
  • Stress

How do antidepressants help?

Certain antidepressants can also treat hot flashes by calming the brain’s temperature-control system.

They DON’T:

  • Replace estrogen
  • Reverse menopause
  • Mean you’re depressed

They DO:

  • Reduce hot flashes
  • Reduce night sweats
  • Provide a non-hormonal treatment option

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2026-10-02

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